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Hotels in Opelousas    Below is only a selection of Opelousas Hotels. Search them all with the search box on the right. Best Western of Opelousas - Opelousas 5791 I-49 S Service Road Opelousas, LA 70570-0726 Information The Best Western of Opelousas, a brand new Best Western located in Opelousas, offers both leisure an More Check Rates Days Inn and Suites Opelousas - Opelousas 5761 I-49 South Service Road Opelousas, LA 70570 Information 4 Sunburst Newest Days Inn in the area Easy access to I-49 Only 20 miles from Lafayette Outdoor pool More Check Rates Holiday Inn Hotel & Suites OPELOUSAS - Opelousas 5696 I-49 NORTH SERVICE RD. Opelousas, LA 70570 Information The Holiday Inn Hotels and Suites Opelousas. Located in the heart of Acadiana, our hotel offers 75 l More Check Rates Americas Best Value Inn - Opelousas 4165 I-49 Service Road South Opelousas, LA 70570 Information Welcome to the Americas Best Value Inn of Opelousas, LA. We are conveniently located off of I-49 at More Check Rates

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